Prof. Chelvam Venkatesh

Total synthesis of biologically important natural products
Design and synthesis of heterocycles and carbocycles of biological importance
Developing new methodologies for construction of C-C and C-X (X =N,O,S,P) bonds
Design, synthesis and diagnostic applications of new targeting ligands for cancers and inflammatory diseases
Drug delivery systems, near-infra red fluorescence, nuclear Imaging and bio-conjugate chemistry
Synthesis of Inhibitors for drug targets

Optimizing affinity to prostate specific membrane antigen by spacer modifications in a tumor spheroid model, Krishnan, M.A.,Pandit, A., Sharma, R., Venkatesh, C., J. Biomol. Struct. Dyn., 0, 000, (2021).
Synthesis of 1-indolyl-3,5,8-substituted g-Carbolines: One-pot solvent-free protocol and biological evaluation, Dudhe, P., Krishnan, M.A., Yadav, K., Roy, D., Venkatasubbaih, K., Pathak, B., Venkatesh, C., Beilstein J. Org. Chem., 00, 000 (2021).
Folate-targeted verrucarin A reduces the number of activated macrophages in a mouse model of acute peritonitis, Venkatesh, C., Doorneweerd, D.D., Xia, W., Putt, K.S., Low, P.S., Bioorg. Med. Chem. Lett., 0, 000, (2021) (in press).
Developing MicroSpherePlatform using a commercial hair brush: An agarose 3D culture platform for deep-tissue imaging of prostate cancer, Krishnan, M.A., Venkatesh, C., ACS Appl. Bio. Mater. 00, 000, (2021).
Targeted QDot nanoprobe for early detection and surgical guidance of prostate cancer, Krishnan, M.A., Yadav, K., Roach, P., Venkatesh, C., Biomater. Sci. 9, 2295-2312, (2021).
Evaluation of the reducing potential of PSMA-containing endosomes by FRET imaging, Venkatesh, C., Shen, J., Putt, K.S., Low, P.S., Cancer Drug Resist., 4, 223-232, (2021).